SODIUM PENTOBARBITAL PENTOBARBITAL - AN OVERVIEW

pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Coadministration of CYP3A4 inducers may lower sufentanil amounts and efficacy, potentially precipitating withdrawal syndrome in individuals who may have formulated Bodily dependence to sufentanil. Discontinuation